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KMID : 0881720160310060399
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Journal of Food Hygiene and Safety
2016 Volume.31 No. 6 p.399 ~ p.405
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Effect of Saekso 2 Corn Kernels and Cobs Extracts on Antioxidant Activity in Rats Fed High Fat-cholesterol Diet
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Lee Ki-Yeon
Kim Jai-Eun
Hong Soo-Young
Kim Tae-hee
Noh Hee-Sun
Kim Si-Chang
Ahn Moon-Sub
Kim Hee-Yeon
Park Jong-yeol
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Abstract
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The objective of this study was to determine the effect of sakso 2 corn kernels and cobs extracts on antioxidant activity in rats fed a high fat-cholesterol diet (HFC) for 2 weeks. 48 male Sprague-Dawley (4-weeks-old) were randomly divided into 6 groups: normal diet (N), HFC (C), HFC and 0.05% kernel extracts of Saekso 2 (T1), HFC and 0.25% kernel extracts of Saekso 2 (T2), HFC and 0.05% cob extracts of Saekso 2 (T3), HFC and 0.25% cob extracts of Saekso 2 (T4). The weight gain in all treatment groups were significantly lower and the food efficiency ratio (FER) in all treatment groups except T3 were lower than C group. Liver index (liver weight/100 g body weight) in N group and T2 were significantly lower than C group. The level of total cholesterol in plasma of N group and T2 were significantly lower than C group and HDL-cholesterol in plasma of N group and T2 were significantly lower than C group. Malondialdehyde (MDA) concentration of thiobarbituric acid reactive substances in N group, T3 and T4 were significantly lower than C group. Activity of catalase (CAT) in all treatment groups were lower than C group. These result suggest that saekso 2 corn kernels and cobs extracts may reduce oxidative damage through the activation of antioxidative defense systems in rats fed high fat-cholesterol diets.
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KEYWORD
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Purple corn, Saekso 2, Antioxidant activity, High fat-cholesterol diet
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